The goal of CASCADE is to accelerate the exploitation of aerial robotics across a wide range of science and industry applications. Through fundamental research and case studies, we will advance the understanding and technologies required to allow routine operation of advanced aerial robotic systems. Common system architectures will be developed and employed together with their associated risk and reliability models. There will also be application specific technology deliverables that meet the needs of current and emerging users of aerial robots linked to the CASCADE case studies. We will shape the technological and regulatory standards upon which a safe and commercially and scientifically vibrant industry can grow.